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中文名稱:聚乙二醇-b-聚己内酯(x/y)
英文名稱:mPEG-b-PCL
由親水性PEG嵌段和疏水性PCL嵌段組成(chéng)的具有生物相容性的兩(liǎng)親性嵌段共聚物。這(zhè)些材料已被(bèi)用作嵌段共聚物表面(miàn)活性劑,以及用于藥物遞送應用的控釋和納米顆粒制劑。通過(guò)控制每個聚合物塊的相對(duì)長(cháng)度,可以制備具有不同性質的定義明确的材料。羟基端接允許對(duì)這(zhè)些材料進(jìn)行簡單的進(jìn)一步化學(xué)改性。
Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These materials have been used as a block copolymer surfactant as well as in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.
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